منابع مشابه
Sickle cell nephropathy.
Herrick [1] was the first to discover sickle cell hemoglobin ( 2 2) with sickle-shaped erythrocytes. In 1910, he described the case of a young black student from the West Indies with severe anemia characterized by “peculiar elongated and sickle-shaped red blood corpuscles.” Herrick also noted a slightly increased volume of urine of low specific gravity and thus observed the most frequent featur...
متن کاملSickle cell nephropathy - a practical approach.
Despite its apparently simple molecular aetiology, sickle cell disease (SCD) has long been known to have a remarkably variable clinical course, with complications involving many organs including the kidneys. Whilst many affected individuals show no evidence of renal involvement into late adulthood, others develop renal dysfunction in childhood or early adult life with a significant proportion e...
متن کاملDISEASE OF THE MONTH Sickle Cell Nephropathy
Epidemiology The presence of renal failure in sickle cell disease (SCD) ranges from 5 to 18% of the total population of SCD patients (1). Powars et al. (2), in a prospective, case-control study of patients with SCD compared with sickle cell hemoglobin C patients, documented 31 (4.2%) patients affected by renal failure. The median age at the time of renal failure was 23.1 yr. Survival time was 4...
متن کاملUpdate on IgM Nephropathy
IgM nephropathy (IgMN) is a relatively recently described, and still a controversial clinicoimmunopathologic entity which presents mainly as idiopathic nephrotic syndrome (INS) in both children and adults (Al-Eisa et al., 1996). The disease, like IgA nephropathy (IgAN), is defined by its immunohistologic features: the presence of immunoglobulin M (IgM) as the sole or dominant immunoglobulin in ...
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ژورنال
عنوان ژورنال: Saudi Journal of Kidney Diseases and Transplantation
سال: 2014
ISSN: 1319-2442
DOI: 10.4103/1319-2442.128495